Race, biochemical disease recurrence, and prostate–specific antigen doubling time after radical prostatectomy
نویسندگان
چکیده
منابع مشابه
Risk prediction models for biochemical recurrence after radical prostatectomy using prostate-specific antigen and Gleason score
Many computer models for predicting the risk of prostate cancer have been developed including for prediction of biochemical recurrence (BCR). However, models for individual BCR free probability at individual time-points after a BCR free period are rare. Follow-up data from 1656 patients who underwent laparoscopic radical prostatectomy (LRP) were used to develop an artificial neural network (ANN...
متن کاملPredictive factors of late biochemical recurrence after radical prostatectomy.
Objective To assess the characteristics of biochemical recurrence in the late period (>5 years after radical prostatectomy) and the differences in the predictors of biochemical recurrence in different periods, we conducted a multicenter retrospective study. Methods We reviewed 478 men who underwent radical prostatectomy for clinically localized prostate cancer. All of the patients were follow...
متن کاملA nomogram predicting long-term biochemical recurrence after radical prostatectomy.
BACKGROUND Men who undergo radical prostatectomy (RP) are at long-term risk of biochemical recurrence (BCR). In this report, the authors have described a model capable of predicting BCR up to at least 15 years after RP that can adjust predictions according to the disease-free interval. METHODS Cox regression was used to model the probability of BCR (a prostate-specific antigen level>0.1 ng/mL...
متن کاملBiochemical recurrence after radical prostatectomy: what does it mean?
BACKGROUND Radical prostatectomy (RP) has been used as the main primary treatment for prostate cancer (PCa) for many years with excellent oncologic results. However, approximately 20-40% of those patients has failed to RP and presented biochemical recurrence (BCR). Prostatic specific antigen (PSA) has been the pivotal tool for recurrence diagnosis, but there is no consensus about the best PSA t...
متن کاملImpact of positive surgical margins on prostatespecific antigen failure after radical prostatectomy in adjuvant treatmentnave patients
for PSA failure ( P < 0.001; hazard ratio, HR, 2.6), need for salvage therapy ( P < 0.001; HR, 2.9) and specific deaths ( P = 0.006; HR, 3.7). The 5-year RFS was 84.4% in men with negative margins compared to 57.5% in the case of PSM. • After stratification by pathological stage and Gleason score, margin status was significantly predictive for PSA failure in pT2 ( P < 0.001), pT3a ( P = 0.001) ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer
سال: 2007
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.23012